REACT incorporates eight Coordination Groups covering specific sectoral activities related to disaster risk management. These groups and the leading agencies are as follows:

Food Security (including nutrition): WFP
Shelter and non-food items: IFRC
Health: WHO
Water and sanitation: UNICEF
Education: UNICEF and Save the Children[1] Sectoral Coordination Groups are expected to meet regularly, and more frequently in a disaster situation, report to the general REACT membership on their activities, and consult with sector members on actions which could affect the REACT Statement of Common Understanding and the policy and practice of REACT.

Each Sectoral Coordination Group establishes its own terms of reference, which are to be provided to REACT. To the degree possible, the terms of reference should reflect the Generic Terms of Reference specific for UN regulations related to clusters.

According to the Tajikistan Inter-Agency Contingency Plan, in the event of a major emergency, the Humanitarian Country Team would trigger the activation of the global cluster approach for Tajikistan in accordance with recommendations made by the Inter Agency Standing Committee. Agencies in-country (and when applicable from the relevant regional delegations) will assume the cluster lead responsibilities accepted in the framework of the global humanitarian response review arrangement.

These responsibilities are to:

Ensure that adequate preparedness measures are taken prior to the crisis
Assume the leadership role in coordination arrangements during the response to the crisis
Ensure that gaps in the response are properly identified and addressed
Act as provider of last resource in case no other partner has the capacity to address the identified gaps

[1]UNICEF and Save the Children in Tajikistan assume sector leadership on an annual rotation basis (UNICEF is the sector lead in 2013)